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Microbial transformations of natural antitumor agents: use of solubilizing agents to improve yields of hydroxylated ellipticines.

Aromatic hydroxylation of the antitumor alkaloid ellipticine by Aspergillus alliaceus results in the formation of both 8- and 9-hydroxyellipticines. Experiments designed to increase yields of microbial hydroxylation focused on enhancing the water solubility of ellipticine in aqueous fermentation med...

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Vydáno v:Appl Environ Microbiol
Hlavní autoři: Chien, M M, Rosazza, J P
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 1980
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC291654/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7425624/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aem.40.4.741-745.1980
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