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Microbial transformations of natural antitumor agents: use of solubilizing agents to improve yields of hydroxylated ellipticines.
Aromatic hydroxylation of the antitumor alkaloid ellipticine by Aspergillus alliaceus results in the formation of both 8- and 9-hydroxyellipticines. Experiments designed to increase yields of microbial hydroxylation focused on enhancing the water solubility of ellipticine in aqueous fermentation med...
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| Published in: | Appl Environ Microbiol |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Microbiology (ASM)
1980
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC291654/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7425624/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aem.40.4.741-745.1980 |
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