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The Localization of APOBEC3H Variants in HIV-1 Virions Determines Their Antiviral Activity
Several members of the human APOBEC3 family of cytidine deaminases can potently restrict retroviruses such as HIV-1. The single-domain APOBEC3H (A3H) is encoded by four haplotypes, of which only A3H haplotype II-RDD (hapII-RDD) restricts HIV-1 efficiently. The goal of this study was to elucidate the...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology (ASM)
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2916534/ https://ncbi.nlm.nih.gov/pubmed/20519396 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00754-10 |
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