Moderate Influence of Human APOBEC3F on HIV-1 Replication in Primary Lymphocytes

Multiple APOBEC3 proteins are expressed in HIV-1 target cells, but their individual contributions to viral suppression when expressed at endogenous levels remain largely unknown. We used an HIV NL4-3 mutant that selectively counteracts APOBEC3G (A3G) but not APOBEC3F (A3F) to dissect the relative co...

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Detalhes bibliográficos
Main Authors: Mulder, Lubbertus C. F., Ooms, Marcel, Majdak, Susan, Smedresman, Jordan, Linscheid, Caitlin, Harari, Ariana, Kunz, Andrea, Simon, Viviana
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937628/
https://ncbi.nlm.nih.gov/pubmed/20592068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02630-09
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