Establishment of an Aerosol Challenge Model of Tuberculosis in Rhesus Macaques and an Evaluation of Endpoints for Vaccine Testing

The establishment of an aerosol challenge model in nonhuman primates (NHPs) for the testing of vaccines against Mycobacterium tuberculosis would assist the global effort to optimize novel vaccination strategies. The endpoints used in preclinical challenge studies to identify measures of disease burd...

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Detalhes bibliográficos
Main Authors: Sharpe, S. A., McShane, H., Dennis, M. J., Basaraba, R. J., Gleeson, F., Hall, G., McIntyre, A., Gooch, K., Clark, S., Beveridge, N. E. R., Nuth, E., White, A., Marriott, A., Dowall, S., Hill, A. V. S., Williams, A., Marsh, P. D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Vaccine Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916246/
https://ncbi.nlm.nih.gov/pubmed/20534795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00079-10
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