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LINE-1 Retrotransposons: Mediators of Somatic Variation in Neuronal Genomes?

LINE-1 (L1) elements are retrotransposons that insert extra copies of themselves throughout the genome using a “copy and paste” mechanism. L1s have contributed ~20% to total human genome content and are able to influence chromosome integrity and gene expression upon reinsertion. Recent studies show...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Singer, Tatjana, McConnell, Michael J., Marchetto, Maria C.N., Coufal, Nicole G., Gage, Fred H.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916067/
https://ncbi.nlm.nih.gov/pubmed/20471112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tins.2010.04.001
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