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LINE-1 Retrotransposons: Mediators of Somatic Variation in Neuronal Genomes?
LINE-1 (L1) elements are retrotransposons that insert extra copies of themselves throughout the genome using a “copy and paste” mechanism. L1s have contributed ~20% to total human genome content and are able to influence chromosome integrity and gene expression upon reinsertion. Recent studies show...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2916067/ https://ncbi.nlm.nih.gov/pubmed/20471112 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tins.2010.04.001 |
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