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Complementary optical and nuclear imaging of caspase-3 activity using combined activatable and radiolabeled multimodality molecular probe

Based on the capability of modulating fluorescence intensity by specific molecular events, we have developed a new multimodal optical-nuclear molecular probe with complementary reporting strategies. The molecular probe (LS498) consists of DOTA for chelating a radionuclide, a near infrared fluorescen...

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Detalhes bibliográficos
Main Authors: Lee, Hyeran, Akers, Walter J., Cheney, Philip P., Edwards, W. Barry, Liang, Kexian, Culver, Joseph P., Achilefu, Samuel
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916017/
https://ncbi.nlm.nih.gov/pubmed/19725712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1117/1.3207156
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