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Near-infrared pH-activatable Fluorescent Probes for Imaging Primary and Metastatic Breast Tumors
Highly tumor selective near-infrared (NIR) pH-activatable probe was developed by conjugating pH-sensitive cyanine dye to a cyclic Arginine-Glycine-Aspartic acid (cRGD) peptide targeting α(v)β(3) integrin (ABIR), a protein that is highly overexpressed in endothelial cells during tumor angiogenesis. T...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3080440/ https://ncbi.nlm.nih.gov/pubmed/21388195 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc100584d |
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