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Dual-radiolabeled nanoparticle SPECT probes for bioimaging

A gold nanoparticle was radiolabeled with (125)I and (111)In and functionalized with an MMP9-cleavable peptide to form a multispectral SPECT imaging contrast agent. Peptide cleavage from the nanoprobe by MMP9 was observed in vitro, and distinct pharmacokinetic properties of the contrast agent were o...

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Vydáno v:Nanoscale
Hlavní autoři: Black, Kvar C.L., Akers, Walter J., Sudlow, Gail, Xu, Baogang, Laforest, Richard, Achilefu, Samuel
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4268305/
https://ncbi.nlm.nih.gov/pubmed/25418982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4nr05269b
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