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A light-gated, potassium-selective glutamate receptor for the optical inhibition of neuronal firing

Genetically targeted light-activated ion channels and pumps make it possible to determine the role of specific neurons in neuronal circuits, information processing and behavior. Here, we describe the development of a K(+)-selective ionotropic glutamate receptor that reversibly inhibits neuronal acti...

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Detalhes bibliográficos
Main Authors: Janovjak, Harald, Szobota, Stephanie, Wyart, Claire, Trauner, Dirk, Isacoff, Ehud Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2915903/
https://ncbi.nlm.nih.gov/pubmed/20581843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.2589
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