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Light-activated ion channels for remote control of neuronal firing
Neurons have ion channels that are directly gated by voltage, ligands and temperature but not by light. Using structure-based design, we have developed a new chemical gate that confers light sensitivity to an ion channel. The gate includes a functional group for selective conjugation to an engineere...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2004
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1447674/ https://ncbi.nlm.nih.gov/pubmed/15558062 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn1356 |
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