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Kinetics of Amyloid β monomer to oligomer exchange by NMR Relaxation
Recent studies implicating non-fibrillar oligomers of the amyloid β (Aβ) peptide as the primary toxic species in Alzheimer’s disease have made Aβ oligomers the subject of intense study. Detailed structural and kinetic characterization of these states, however, has been difficult. Here we use NMR rel...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2915839/ https://ncbi.nlm.nih.gov/pubmed/20604554 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja1048253 |
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