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Kinetics of Amyloid β monomer to oligomer exchange by NMR Relaxation

Recent studies implicating non-fibrillar oligomers of the amyloid β (Aβ) peptide as the primary toxic species in Alzheimer’s disease have made Aβ oligomers the subject of intense study. Detailed structural and kinetic characterization of these states, however, has been difficult. Here we use NMR rel...

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Bibliografiset tiedot
Päätekijät: Fawzi, Nicolas L., Ying, Jinfa, Torchia, Dennis A., Clore, G. Marius
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2915839/
https://ncbi.nlm.nih.gov/pubmed/20604554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja1048253
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