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PCNA-coupled p21 degradation after DNA damage: the exception that confirms the rule?

While many are the examples of DNA damaging treatments that induce p21 accumulation, the conception of p21 upregulation as the universal response to genotoxic stress has come to an end. Compelling evidences have demonstrated the existence of converging signals that negatively regulate p21 bellow bas...

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Detalhes bibliográficos
Main Authors: Soria, Gastón, Gottifredi, Vanesa
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2915755/
https://ncbi.nlm.nih.gov/pubmed/20060369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2009.12.003
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