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Collateral DNA Damage Produced by Genome-Editing Drones: Exception or Rule?

In the recent issue of Nature Biotechnology, Frock et al. (2015) developed an elegant technique to capture translocation partners that can be utilized to determine off-target regions of genome-editing endonucleases as well as endogenous mutators at nucleotide resolution.

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Bibliografiske detaljer
Udgivet i:Mol Cell
Main Authors: Canela, Andres, Stanlie, Andre, Nussenzweig, André
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6289255/
https://ncbi.nlm.nih.gov/pubmed/26000841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.05.012
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