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DNAJB6 Induces Degradation of β-Catenin and Causes Partial Reversal of Mesenchymal Phenotype

We showed that expression of MRJ (DNAJB6) protein is lost in invasive ductal carcinoma, and restoration of MRJ(L) restricts malignant behavior of breast cancer and melanoma cells. However, the signaling pathways influenced by MRJ(L) are largely unknown. Our observations revealed that MRJ(L) expressi...

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書誌詳細
主要な著者: Mitra, Aparna, Menezes, Mitchell E., Shevde, Lalita A., Samant, Rajeev S.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2010
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2915705/
https://ncbi.nlm.nih.gov/pubmed/20522561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.094847
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