Identification of an Htm1 (EDEM)-dependent, Mns1-independent Endoplasmic Reticulum-associated Degradation (ERAD) Pathway in Saccharomyces cerevisiae: APPLICATION OF A NOVEL ASSAY FOR GLYCOPROTEIN ERAD

Endoplasmic reticulum (ER)-associated degradation (ERAD) is a quality control system for newly synthesized proteins in the ER; nonfunctional proteins, which fail to form their correct folding state, are then degraded. The cytoplasmic peptide:N-glycanase is a deglycosylating enzyme that is involved i...

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Main Authors: Hosomi, Akira, Tanabe, Kaori, Hirayama, Hiroto, Kim, Ikjin, Rao, Hai, Suzuki, Tadashi
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2010
נושאים:
Cell Biology
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2915668/
https://ncbi.nlm.nih.gov/pubmed/20511219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.095919
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