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Bypass of glycan-dependent glycoprotein delivery to ERAD by up-regulated EDEM1
Trimming of mannose residues from the N-linked oligosaccharide precursor is a stringent requirement for glycoprotein endoplasmic reticulum (ER)-associated degradation (ERAD). In this paper, we show that, surprisingly, overexpression of ER degradation–enhancing α-mannosidase-like protein 1 (EDEM1) or...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The American Society for Cell Biology
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3204057/ https://ncbi.nlm.nih.gov/pubmed/21917589 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E10-12-0944 |
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