Endoplasmic Reticulum-associated Degradation (ERAD) and Free Oligosaccharide Generation in Saccharomyces cerevisiae

In Saccharomyces cerevisiae, proteins with misfolded lumenal, membrane, and cytoplasmic domains are cleared from the endoplasmic reticulum (ER) by ER-associated degradation (ERAD)-L, -M, and -C, respectively. ERAD-L is N-glycan-dependent and is characterized by ER mannosidase (Mns1p) and ER mannosid...

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Autores principales: Chantret, Isabelle, Kodali, Vidya P., Lahmouich, Chaïmaâ, Harvey, David J., Moore, Stuart E. H.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
Materias:
Glycobiology and Extracellular Matrices
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308887/
https://ncbi.nlm.nih.gov/pubmed/21979948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.251371
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