Evaluation of BACE1 Silencing in Cellular Models

Beta-secretase (BACE1) is the major enzyme participating in generation of toxic amyloid-beta (Aβ) peptides, identified in amyloid plaques of Alzheimer's disease (AD) brains. Its downregulation results in decreasing secretion of Aβ. Thus, BACE1 silencing by RNAi represents possible strategy for...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Sierant, Malgorzata, Kubiak, Katarzyna, Kazmierczak-Baranska, Julia, Warashina, Masaki, Kuwabara, Tomoko, Nawrot, Barbara
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: SAGE-Hindawi Access to Research 2009
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2915613/
https://ncbi.nlm.nih.gov/pubmed/20721293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2009/257403
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