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Acetazolamide and midazolam act synergistically to inhibit neuropathic pain

Treatment of neuropathic pain is a major clinical challenge that has been met with minimal success. After peripheral nerve injury, a decrease in the expression of the K–Cl cotransporter KCC2, a major neuronal Cl(−) extruder, leads to pathologic alterations in GABA(A) and glycine receptor function in...

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Hlavní autoři: Asiedu, Marina, Ossipov, Michael H., Kaila, Kai, Price, Theodore J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2914558/
https://ncbi.nlm.nih.gov/pubmed/20007010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pain.2009.11.015
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