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Lessons from Free Energy Simulations of δ-Opioid Receptor Homodimers Involving the Fourth Transmembrane Helix

[Image: see text] Several G protein-coupled receptors (GPCRs), including opioid receptors δOR, μOR, and κOR, have been reported to form stable dimers or oligomers in lipid bilayers and cell membranes. This notion has been recently challenged by imaging data supporting a transient nature of GPCR asso...

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Hlavní autoři: Provasi, Davide, Johnston, Jennifer M., Filizola, Marta
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2010
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2914489/
https://ncbi.nlm.nih.gov/pubmed/20617813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi100686t
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