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Bioactive Conformations of Two Seminal Delta Opioid Receptor Penta-peptides Inferred from Free-Energy Profiles

Delta-opioid (DOP) receptors are members of the G protein-coupled receptor (GPCR) sub-family of opioid receptors, and are evolutionarily related, with homology exceeding 70%, to cognate mu-opioid (MOP), kappa-opioid (KOP), and nociceptin opioid (NOP) receptors. DOP receptors are considered attractiv...

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Detalhes bibliográficos
Main Authors: Scarabelli, Guido, Provasi, Davide, Negri, Ana, Filizola, Marta
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3812360/
https://ncbi.nlm.nih.gov/pubmed/23564013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bip.22251
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