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Mutational clusters generated by non-processive polymerases: a case study using DNA polymerase ß in vitro

Available DNA mutational spectra reveal that the number of mutants with multiple mutations (“multiples”) is usually greater than expected from a random distribution of mutations among mutants. These overloads imply the occurrence of non-random clusters of mutations, probably generated during episode...

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Autors principals: García-Villada, Libertad, Drake, John W.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2914196/
https://ncbi.nlm.nih.gov/pubmed/20627824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2010.05.002
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