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Mutational clusters generated by non-processive polymerases: a case study using DNA polymerase ß in vitro
Available DNA mutational spectra reveal that the number of mutants with multiple mutations (“multiples”) is usually greater than expected from a random distribution of mutations among mutants. These overloads imply the occurrence of non-random clusters of mutations, probably generated during episode...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2914196/ https://ncbi.nlm.nih.gov/pubmed/20627824 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2010.05.002 |
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