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DNA Polymerase zeta Generates Clustered Mutations During Bypass of Endogenous DNA Lesions in Saccharomyces cerevisiae
Multiple sequence changes that are simultaneously introduced in a single DNA transaction have a higher probability of altering gene function than do single base substitutions. DNA polymerase zeta (Pol ζ) has been shown to introduce such clustered mutations under specific selective and/or DNA damage-...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3678557/ https://ncbi.nlm.nih.gov/pubmed/22965922 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/em.21728 |
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