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DNA Polymerase zeta Generates Clustered Mutations During Bypass of Endogenous DNA Lesions in Saccharomyces cerevisiae

Multiple sequence changes that are simultaneously introduced in a single DNA transaction have a higher probability of altering gene function than do single base substitutions. DNA polymerase zeta (Pol ζ) has been shown to introduce such clustered mutations under specific selective and/or DNA damage-...

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Detaylı Bibliyografya
Asıl Yazarlar: Stone, Jana E., Lujan, Scott A., Kunkel, Thomas A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3678557/
https://ncbi.nlm.nih.gov/pubmed/22965922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/em.21728
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