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The Three Faces of Riboviral Spontaneous Mutation: Spectrum, Mode of Genome Replication, and Mutation Rate

Riboviruses (RNA viruses without DNA replication intermediates) are the most abundant pathogens infecting animals and plants. Only a few riboviral infections can be controlled with antiviral drugs, mainly because of the rapid appearance of resistance mutations. Little reliable information is availab...

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Main Authors: García-Villada, Libertad, Drake, John W.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3405988/
https://ncbi.nlm.nih.gov/pubmed/22844250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002832
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