טוען...
Chk2*1100delC Acts in Synergy with the Ron Receptor Tyrosine Kinase to Accelerate Mammary Tumorigenesis in Mice
The CHEK2 (Chk2 in mice) polymorphic variant, CHEK2*1100delC, leads to genomic instability and is associated with an increased risk for breast cancer. The Ron receptor tyrosine kinase is overexpressed in a large fraction of human breast cancers. Here, we asked whether the low penetrance Chk2*1100del...
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| Main Authors: | , , , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2010
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2914152/ https://ncbi.nlm.nih.gov/pubmed/20434834 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2010.04.011 |
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