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Conditional Deletion of β-Catenin in Mammary Epithelial Cells of Ron Receptor, Mst1r, Overexpressing Mice Alters Mammary Tumorigenesis

The Ron receptor tyrosine kinase (macrophage stimulating 1 receptor) is overexpressed in approximately 50% of human breast cancers. Transgenic mice overexpressing Ron in the mammary epithelium [mouse mammary tumor virus driven (MMTV)-Ron expressing mice] develop mammary tumors that exhibit up-regula...

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Detalhes bibliográficos
Main Authors: Wagh, Purnima K., Zinser, Glendon M., Gray, Jerilyn K., Shrestha, Archana, Waltz, Susan E.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3359604/
https://ncbi.nlm.nih.gov/pubmed/22474186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2011-1543
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