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Uptake of pramipexole by human organic cation transporters
Pramipexole is a hydrophilic, weakly basic drug, but exhibits high oral bioavailability in humans (> 90%). In rats, rOct1 and rOct2 contribute towards pramipexole excretion into urine. The objective of this study was to assess whether pramipexole is a substrate for human OCT1-3. In vitro uptake s...
Gorde:
| Egile Nagusiak: | , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2010
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2914150/ https://ncbi.nlm.nih.gov/pubmed/20496886 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp100036b |
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