A carregar...

Uptake of pramipexole by human organic cation transporters

Pramipexole is a hydrophilic, weakly basic drug, but exhibits high oral bioavailability in humans (> 90%). In rats, rOct1 and rOct2 contribute towards pramipexole excretion into urine. The objective of this study was to assess whether pramipexole is a substrate for human OCT1-3. In vitro uptake s...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Diao, Lei, Shu, Yan, Polli, James E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2914150/
https://ncbi.nlm.nih.gov/pubmed/20496886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp100036b
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!