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Novel Inhibitors of Human Organic Cation/Carnitine Transporter (hOCTN2) via Computational Modeling and In Vitro Testing
PURPOSE: The objective was to elucidate the inhibition requirements of the human Organic Cation/Carnitine Transporter (hOCTN2). METHODS: Twenty-seven drugs were screened initially for their potential to inhibit uptake of L-carnitine into a stably transfected hOCTN2-MDCK cell monolayer. A HipHop comm...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2891772/ https://ncbi.nlm.nih.gov/pubmed/19437106 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-009-9905-3 |
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