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Injectable pH- and temperature-responsive poly(N-isopropylacrylamide-co-propylacrylic acid) copolymers for delivery of angiogenic growth factors

A new sharply pH- and temperature-responsive hydrogel system was designed for delivering drugs to regions of local acidosis, as found in wound healing, tumor sites, or sites of ischemia. The reversible addition fragmentation chain transfer (RAFT) polymerization technique was used to synthesize copol...

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Main Authors: Garbern, Jessica C., Hoffman, Allan S., Stayton, Patrick S.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2914148/
https://ncbi.nlm.nih.gov/pubmed/20509687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bm100318z
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