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Delivery of basic fibroblast growth factor with a pH-responsive, injectable hydrogel to improve angiogenesis in infarcted myocardium

A pH- and temperature-responsive, injectable hydrogel has been designed to take advantage of the acidic microenvironment of ischemic myocardium. This system can improve therapeutic angiogenesis methods by providing spatio-temporal control of angiogenic growth factor delivery. The pH- and temperature...

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Detalhes bibliográficos
Main Authors: Garbern, Jessica C., Minami, Elina, Stayton, Patrick S., Murry, Charles E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3026890/
https://ncbi.nlm.nih.gov/pubmed/21186056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2010.11.075
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