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Sulindac and Its Metabolites Inhibit Multiple Transport Proteins in Rat and Human Hepatocytes
Sulindac is a commonly used nonsteroidal anti-inflammatory drug. This study tested the hypothesis that sulindac-mediated drug–drug interactions and/or hepatotoxicity may be caused, in part, by inhibition of proteins responsible for the hepatic transport of drugs and/or bile acids by sulindac and/or...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Pharmacology and Experimental Therapeutics
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2913772/ https://ncbi.nlm.nih.gov/pubmed/20430841 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.110.165852 |
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