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Neuroprotective Effects of Pyruvate Following NMDA-Mediated Excitotoxic Insults in Hippocampal Slices

The activation of N-methyl-D-aspartate (NMDA) receptors and subsequent release of nitric oxide (NO) are likely contributors to the delayed neuronal damage that accompanies ischemia and other neurodegenerative conditions. NMDA receptor antagonists and inhibitors of NO synthesis, however, are of limit...

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Detalhes bibliográficos
Main Authors: Izumi, Yukitoshi, Zorumski, Charles F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2913700/
https://ncbi.nlm.nih.gov/pubmed/20452397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2010.04.078
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