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Neuroprotective Effects of Pyruvate Following NMDA-Mediated Excitotoxic Insults in Hippocampal Slices

The activation of N-methyl-D-aspartate (NMDA) receptors and subsequent release of nitric oxide (NO) are likely contributors to the delayed neuronal damage that accompanies ischemia and other neurodegenerative conditions. NMDA receptor antagonists and inhibitors of NO synthesis, however, are of limit...

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Autori principali: Izumi, Yukitoshi, Zorumski, Charles F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2913700/
https://ncbi.nlm.nih.gov/pubmed/20452397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2010.04.078
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