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Neuroprotective Effects of Pyruvate Following NMDA-Mediated Excitotoxic Insults in Hippocampal Slices

The activation of N-methyl-D-aspartate (NMDA) receptors and subsequent release of nitric oxide (NO) are likely contributors to the delayed neuronal damage that accompanies ischemia and other neurodegenerative conditions. NMDA receptor antagonists and inhibitors of NO synthesis, however, are of limit...

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Bibliografiske detaljer
Main Authors: Izumi, Yukitoshi, Zorumski, Charles F.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2913700/
https://ncbi.nlm.nih.gov/pubmed/20452397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2010.04.078
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