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Zinc Modulates Bidirectional Hippocampal Plasticity by Effects on NMDA Receptors
Zinc has complex effects on NMDA receptors (NMDARs) and may be an endogenous modulator of synaptic plasticity. In the CA1 region of rat hippocampal slices, we observed that low micromolar concentrations of zinc depress NMDAR synaptic responses by 40–50% and inhibit long-term depression (LTD) but not...
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| Publicado no: | J Neurosci |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6673951/ https://ncbi.nlm.nih.gov/pubmed/16822975 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1258-06.2006 |
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