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Zinc Modulates Bidirectional Hippocampal Plasticity by Effects on NMDA Receptors
Zinc has complex effects on NMDA receptors (NMDARs) and may be an endogenous modulator of synaptic plasticity. In the CA1 region of rat hippocampal slices, we observed that low micromolar concentrations of zinc depress NMDAR synaptic responses by 40–50% and inhibit long-term depression (LTD) but not...
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| Publicat a: | J Neurosci |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Society for Neuroscience
2006
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6673951/ https://ncbi.nlm.nih.gov/pubmed/16822975 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1258-06.2006 |
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