Nalaganje...
Constitutively active Stat5b in CD4(+) T cells inhibits graft-versus-host disease lethality associated with increased regulatory T-cell potency and decreased T effector cell responses
Overexpression of a constitutively active form of Stat5b (Stat5b-CA) increases regulatory T cells (Tregs). We show that Stat5b-CA transgenic (TG) CD4(+) T cells had a markedly reduced graft-versus-host disease (GVHD) capacity versus wild-type (WT) T cells. Stat5b-CA TG versus WT CD4(+) T cells had a...
Shranjeno v:
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society of Hematology
2010
|
| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2913456/ https://ncbi.nlm.nih.gov/pubmed/20442366 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-11-252825 |
| Oznake: |
Označite
Brez oznak, prvi označite!
|