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Germinal Center T Follicular Helper Cell IL-4 Production Is Dependent on Signaling Lymphocytic Activation Molecule Receptor (CD150)

CD4 T cell help is critical for the generation and maintenance of germinal centers (GCs), and T follicular helper (T(FH)) cells are the CD4 T cell subset required for this process. Signaling lymphocytic activation molecule (SLAM)-associated protein (SAP [SH2D1A]) expression in CD4 T cells is essenti...

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Detalhes bibliográficos
Main Authors: Yusuf, Isharat, Kageyama, Robin, Monticelli, Laurel, Johnston, Robert J., DiToro, Daniel, Hansen, Kyle, Barnett, Burton, Crotty, Shane
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2913439/
https://ncbi.nlm.nih.gov/pubmed/20525889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0903505
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