Morphine Suppresses Tumor Angiogenesis through a HIF-1α/p38MAPK Pathway

Morphine, a highly potent analgesic agent, is frequently prescribed for moderate to severe cancer pain. In this study, morphine was administered at a clinically relevant analgesic dose to assess tumor cell-induced angiogenesis and subcutaneous tumor growth in nude mice using mouse Lewis lung carcino...

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Main Authors: Koodie, Lisa, Ramakrishnan, Sundaram, Roy, Sabita
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Investigative Pathology 2010
Assuntos:
Regular Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2913371/
https://ncbi.nlm.nih.gov/pubmed/20616349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090621
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