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Morphine Decreases Bacterial Phagocytosis by Inhibiting Actin Polymerization through cAMP-, Rac-1-, and p38 MAPK-Dependent Mechanisms

Morphine increases the susceptibility to opportunistic infection by attenuating bacterial clearance through inhibition of Fcγ receptor (FcgR)–mediated phagocytosis. Mechanisms by which morphine inhibits this process remain to be investigated. Actin polymerization is essential for FcgR-mediated inter...

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Bibliografiska uppgifter
Huvudupphovsmän: Ninković, Jana, Roy, Sabita
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Investigative Pathology 2012
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3349892/
https://ncbi.nlm.nih.gov/pubmed/22248582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.11.034
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