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Acacetin inhibits VEGF expression, tumor angiogenesis and growth through AKT/HIF-1α pathway

Acacetin (5,7-dihydroxy-4′-methoxyflavone) is a flavone compound, some of which have anti-cancerous effects. Vascular endothelial growth factor (VEGF) plays an important role in angiogenesis and tumor growth. In this study, we found that acacetin decreased the steady level of VEGF mRNA level and inh...

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Bibliografische gegevens
Hoofdauteurs: Liu, Ling-Zhi, Jing, Yi, Jiang, Lisa L., Jiang, Xiu-E, Jiang, Yue, Rojanasakul, Yongyut, Jiang, Bing-Hua
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3224790/
https://ncbi.nlm.nih.gov/pubmed/21893035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2011.08.091
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