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Acacetin inhibits VEGF expression, tumor angiogenesis and growth through AKT/HIF-1α pathway
Acacetin (5,7-dihydroxy-4′-methoxyflavone) is a flavone compound, some of which have anti-cancerous effects. Vascular endothelial growth factor (VEGF) plays an important role in angiogenesis and tumor growth. In this study, we found that acacetin decreased the steady level of VEGF mRNA level and inh...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3224790/ https://ncbi.nlm.nih.gov/pubmed/21893035 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2011.08.091 |
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