Morphine Inhibits Migration of Tumor-Infiltrating Leukocytes and Suppresses Angiogenesis Associated with Tumor Growth in Mice

Tumor cells secrete factors that stimulate the migration of peripheral blood leukocytes and enhance tumor progression by affecting angiogenesis. In these studies, we investigated the effect of morphine, a known immunosuppressant, on leukocyte migration and recruitment to conditioned media derived fr...

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Detalhes bibliográficos
Main Authors: Koodie, Lisa, Yuan, Hongyan, Pumper, Jeffery A., Yu, Haidong, Charboneau, Richard, Ramkrishnan, Sundaram, Roy, Sabita
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2014
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3969995/
https://ncbi.nlm.nih.gov/pubmed/24495739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2013.12.019
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