Morphine Inhibits Migration of Tumor-Infiltrating Leukocytes and Suppresses Angiogenesis Associated with Tumor Growth in Mice

Tumor cells secrete factors that stimulate the migration of peripheral blood leukocytes and enhance tumor progression by affecting angiogenesis. In these studies, we investigated the effect of morphine, a known immunosuppressant, on leukocyte migration and recruitment to conditioned media derived fr...

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Main Authors: Koodie, Lisa, Yuan, Hongyan, Pumper, Jeffery A., Yu, Haidong, Charboneau, Richard, Ramkrishnan, Sundaram, Roy, Sabita
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2014
Teme:
Regular Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3969995/
https://ncbi.nlm.nih.gov/pubmed/24495739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2013.12.019
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