Morphine Inhibits Migration of Tumor-Infiltrating Leukocytes and Suppresses Angiogenesis Associated with Tumor Growth in Mice

Tumor cells secrete factors that stimulate the migration of peripheral blood leukocytes and enhance tumor progression by affecting angiogenesis. In these studies, we investigated the effect of morphine, a known immunosuppressant, on leukocyte migration and recruitment to conditioned media derived fr...

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Autores principales: Koodie, Lisa, Yuan, Hongyan, Pumper, Jeffery A., Yu, Haidong, Charboneau, Richard, Ramkrishnan, Sundaram, Roy, Sabita
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Investigative Pathology 2014
Materias:
Regular Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3969995/
https://ncbi.nlm.nih.gov/pubmed/24495739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2013.12.019
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