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Tubular Overexpression of Transforming Growth Factor-β1 Induces Autophagy and Fibrosis but Not Mesenchymal Transition of Renal Epithelial Cells
We recently showed in a tetracycline-controlled transgenic mouse model that overexpression of transforming growth factor (TGF)-β1 in renal tubules induces widespread peritubular fibrosis and focal degeneration of nephrons. In the present study we have analyzed the mechanisms underlying these phenome...
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| Główni autorzy: | , , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Society for Investigative Pathology
2010
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2913362/ https://ncbi.nlm.nih.gov/pubmed/20616344 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.091012 |
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